Tolfenamic Acid: A Modifier of the Tau Protein and its Role in Cognition and Tauopathy

In this study, treatment with tolfenamic acid  improved spatial learning deficits and memory impairments in young and aged hTau mice along with reductions in total tau as well as in site specific hyperphosphorylation of tau. Furthermore immunohistochemical analysis for phosphorylated tau protein revealed reduced staining in the frontal cortex, hippocampus, and striatum in animals treated with TA.

NeuroTau, Inc. is a biotech company, formed in 2017, that focuses on developing drugs that target the disruption or decay of the important neurobiological protein called Tau

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